To investigate early epigenetic signatures of dysregulated genes in HD mouse striatum at cell type-specific levels, we delineated neuronal and non-neuronal (glial) super enhancer-regulated genes using H3K27ac and H3K27me3 ChIPseq data generated on WT NeuN+ and NeuN− striatal nuclei (Fig. 1c, Supplementary Fig. 2 and Supplementary Data 1). Here, RBFOX3 is linked to Huntington disease.