RBFOX3 and Huntington disease: To specify temporal dynamics of epigenetic changes in HD neurons and glial cells, we generated H3K27ac and H3K27me3 ChIP-seq data in NeuN+ and NeuN− WT mouse striatal nuclei using the fluorescence activated nuclear sorting (FANS) approach18 (Fig. 1c and Supplementary Figs. 2, 7a), which allowed the identification of neuronal and non-neuronal (essentially glial) specific enhancers (Supplementary Data 1).