CD274 and non-small cell lung carcinoma: While two studies indicated that the expression level of PD-L1 was not closely associated to the count of TILs, such as CD4, CD8, and Foxp3-regulatory T cells (Tregs) in NSCLC [8, 9], one study reported a statistically significant correlation between the maximum standardized uptake value (SUVmax) and expression of CD8 TILs, CD163 tumor-associated macrophages, and Tregs [27].