IL6 and colitis: For serum MDA and serum IL-6, pairwise analysis revealed that all treatment groups [except low-dose 6-paradol (50 mg/kg)] significantly reversed the changes in these parameters compared to the untreated acetic acid-induced colitis group (p < 0.001), but they did not reach levels comparable to the normal control except for the high-dose 6-paradol (200 mg/kg) and sulfasalazine (500 mg/kg) groups.