TNF and COVID-19: “Inflammatory response,” “IL6 and TNFA signaling” is an attribute of both G1 and G2, to a lesser degree of G5, also tuberculosis/HIV, and to some extent of sepsis and influenza A. More prominently enriched in sepsis were “complement,” “coagulation,” “heme metabolism,” and “glycolysis” — shared by COVID-19 G1+G3, whereas “oxidative phosphorylation” and “mTORC1 signaling” were seen for all four influenza strains, chikungunya, and Zika virus infections — shared to some extent with COVID-19 G3+G4.