TNFRSF12A and posterior cortical atrophy: In the aforementioned study, we observed that in patients with high-risk PCa, the decrease in sTWEAK levels in semen was accompanied by an increase in Fn14 mRNA levels in seminal cell sediment, pointing to an active process of ligand–receptor interaction that may favor cell proliferation and migration, as described in PCa cell models [17,18].