Concerning the ABCB1 gene, Ing Lorenzini’s team reported in 2016 a case of rivaroxaban-induced hemorrhage in a patient with homozygous mutated TT genotype for rs2032582 and rs1045642 [20], which is in line with the results highlighted by Xie et al. in 2018 (higher peak concentrations for these homozygous mutated genotypes, as well as AUC for rs1045642) [25]. This evidence concerns the gene ABCB1 and hemorrhage.