HMGA2 and thyroid tumor: We previously proposed a new diagnostic algorithm that allows identification and classification of malignancy markers of thyroid tumors in cytological preparations of biopsy material through an analysis of the following molecular panel: the HMGA2 oncogene; microRNA (miRNA, miR) 146b, miR-221, and miR-375; the ratio of mitochondrial DNA (mtDNA) to nuclear DNA (nDNA); and BRAFV600E mutation detection [15,16].