For example, the Afirma Genomic Sequencing Classifier (GSC) includes eight components: modules of the parathyroid gland and of medullary cancer, BRAFV600E mutation detection (PTC), detection of RET–PTC1 and RET–PTC3 translocations (PTC), a follicular content index (identifies samples with a low thyroid gland cell count), an ensemble model (a suspected cancer/benign sample), a Hürthle cell index, and the Hürthle cell neoplasm index [13]. This evidence concerns the gene RET and cancer.