Previous reports have shown that gastric differentiation program was triggered in murine lung ADC following NKX2‐1 deletion, which involved the interaction of NKX2‐1 and FOXA1/FOXA2 to re‐program FOXA1/FOXA2 binding sites and preferential activation of certain target genes (Minoo et al, 2007; Gao et al, 2008; Wederell et al, 2008; Camolotto et al, 2018). This evidence concerns the gene FOXA2 and medical procedure.