As shown in Figure 7A‐C, after transfection with si‐Piezo1, the expression levels of Piezo1, HIF‐1α, VEGF and vimentin were notably decreased, whereas the mRNA expression levels of E‐cadherin were significantly elevated in peritoneal metastatic tumour tissues at the mRNA and protein levels. This evidence concerns the gene PIEZO1 and neoplasm.