TSLPR was expressed on naïve (CD44low) CD8+ T cells, with high expression on virus-specific CD8+ T cells in both the lungs and spleen by day six post-infection (Figure 1A), with a subsequent decrease evident at days 14 and 33 (Figure 1A), suggesting that TSLP might directly act on virus-specific CD8+ T cells, and indeed increased Tslp mRNA expression has been observed during influenza infection (Shane and Klonowski, 2014; Yadava et al., 2013). This evidence concerns the gene CRLF2 and infection.