In another study, transferrin was used to enhance the tumor penetration of polysulfamide‐based (poly(2‐((2‐(methacryloyloxy)ethyl) dimethylammonio)acetyl) (phenylsulfonyl) amide) nanogels.[91] These nanogels showed a favorable penetration ability in 3D tumor spheroids. This evidence concerns the gene TF and neoplasm.