GAD1 and stiff-person syndrome: Fifteen days after the infusion of rituximab, stiffness began to resolve, and the patient was able to shower herself for the first time in more than two years. Anti-GAD titers became undetectable 17 days after treatment. After the sixth week, she was re-admitted and treated with another course of rituximab and mycophenolate mofetil. Her condition improved and was able to stand and walk with help, sit, and shower. This report is considered the first of the successful use of rituximab in the treatment of SPS.