It is a complete humanized monoclonal antibody that hamper various isoform of VEGF thereby regresses the Neovessels and stop episodes of rebleeding during the vitreous hemorrhage clearing process.3 As the duration of effect of anti VEGF is short, so they need to be repeated.3,4,5 Intravitreal Bevacizumab (IVB) is beneficial in case of neovascular glaucoma, persistent vitreous hemorrhage and before vitrectomy.4 This evidence concerns the gene VEGFA and vitreous hemorrhage.