REN and Myocardial fibrosis: It has powerful diuretic, natriuretic, and vasodilator functions.7,8 Natriuretic peptide increases cyclic guanosine monophosphate by binding with its corresponding receptor in the body, thus expanding the arteries and veins of patients, mediating a series of physiological effects, inhibiting the sympathetic nervous system and renin-angiotensin-aldosterone system, effectively reducing myocardial fibrosis, suppressing the expression of tissue factor in vascular endothelial cells, and preventing thrombosis.