It has been reported that the operation can cause temporary immunity inhibition in the body, where the changes in T lymphocytes are most obvious: decreases in CD3+, CD4+ and CD4+/CD8+ decrease and increases in CD8+.21,22 This indicates that laparoscopic surgery can protect the immunologic mechanism of the body and significantly reduce postoperative infection and other complications. The gene discussed is CD4; the disease is infection.