Andreassen et al. 76, on behalf of the International Radiogenomics Consortium, conducted an individual patient data meta-analysis to assess the relationship between the ATM rs1801516 SNP and toxicity after radiotherapy in 5456 breast and prostate cancer patients from 17 different cohorts (breast cancer, n=2759; prostate cancer, n=2697), concluding that there is an association between the ATM rs1801516 Asn allele and increased risk of radiation-induced toxicity (odds ratio of approximately 1.5 for acute toxicity and 1.2 for late toxicity). The gene discussed is ATM; the disease is Familial prostate cancer.