The same COX multivariate analysis was also performed for OS, and more lymph node metastasis (HR = 2.991, P = 0.000), larger tumor size (HR = 2.075, P = 0.003), and vascular invasion (HR = 6.759, P = 0.009) could increase the risk of death; while higher SLCO1B3 expression (HR = 0.574, P = 0.018) and positive PR (HR = 0.369, P = 0.001) could reduce the risk of death, which were independent prognostic factor for OS. This evidence concerns the gene SLCO1B3 and metastatic malignant neoplasm in the lymph nodes.