SDC1 and endothelial dysfunction: We, therefore, measured syndecan-1 (Fig. 2B) and heparan sulfate (Fig. 2C) concentrations at baseline and in the perfusate during EVLP, as indicators of injury and inflammation, which is mostly related to glycocalyx shedding that is the first step in endothelial dysfunction; we observed that lungs form PAH and IPF, which have the most significant damage of the endothelial, have higher glycocalyx in the perfusion solution.