Following colitis induction, GAL2R-KO and GAL2R-WT mice exhibited similar changes to the gut microbiome as observed in GAL3R-KO and GAL3R-WT mice; however, gene numbers were similar between DSS-treated GAL2R-KO and GAL2R-WT mice (Fig. 7). The gene discussed is GALR2; the disease is colitis.