PDLIM7 and nasopharyngeal carcinoma: In addition, 13C-labeled pyruvate and lactate levels were markedly elevated, whereas 13C-labeled metabolite levels of the tricarboxylic acid cycle, including 13C-citrate, 13C-α-ketoglutarate, 13C-fumarate, and 13C-malate were significantly decreased.67 Importantly, our latest findings revealed that LMP1-positive NPC cells have a powerful mitochondrial fission function to sustain metabolic changes.