LINC00460 and cancer: LINC00460 contributes to the progression of NPC by regulating the miR-149-5p/IL-6 signaling pathway, suggesting that LINC00460 could be regarded as a novel prognostic biomarker and therapeutic target in NPC diagnosis and treatment.288 CircRNA ZNF609 (circ-ANF609) and miR-188 have been, respectively, reported to play a pro-cancer and anticancer role in NPC.