NFKB1 and bipolar disorder: In summary, the majority of bipolar disorder subjects have (1) elevated mRNA levels for NF-κB family members, initiation receptors, and NF-κB-regulated transcripts, (2) lower mRNA levels for an NF-κB inhibitor, (3) positive correlations between NF-κB-related markers, and (4) negative correlations between these NF-κB-related markers and an NF-κB inhibitor.