Similarly, miR-196a193 and miR-451 determine RR via targeting annexin-1 (ANXA1) and RAS related protein 14 (RAB14), respectively, in HNSCC.194 Similar to miRNA-214, miR-205195 and miR-296-5p196 via targeting PTEN promote RR in NPC. Here, ANXA1 is linked to head and neck squamous cell carcinoma.