LYZL1 and Crohn disease: By data mining of the previous results on microbiome quantitative trait loci (QTL) (Table 3), it was shown that the risk genotypes of rs1889714 (LYZL1) in IgAN were negatively correlated with the abundance of Dialister, which has been reported to be significantly decreased in patients with IgA vasculitis or Crohn’s disease (19, 20).