In LN patients, urinary analysis showed 24-h urinary total protein excretion and numbers of red blood cell, white blood cell, and serology displayed levels of complements, erythrocyte sedimentation rate, serum creatine, albumin and routine blood indexes, the increased score of systemic lupus erythematous activity of disease indices (SLEDAI), and different severity of renal dysfunction. The gene discussed is ALB; the disease is lobular neoplasia.