However, another study identified an SNP within the intronic region of IL17RD in psoriasis [70], suggesting that alterations in either regulatory regions, posttranscriptional splicing, or modulation of transcript level via miRNAs might affect its mRNA stability in psoriasis, and consequently of IL23. Further, SNPs in IL17RD and IL17RA were also found to be associated with Crohn’s disease [71], however the exact mechanistic role of IL17RD in this context is still unknown. Here, IL17RD is linked to Crohn disease.