Meanwhile, univariate survival analysis indicated that low SDPR expression was associated with the shorter OS in NSCLC patients as well as in KRAS-mutant group (KRAS-mutant lung adenocarcinoma, P < 0.05, hazard ratio [HR] = 0.7; lung adenocarcinoma, P < 0.05, hazard ratio [HR] = 0.7; Table 1). This evidence concerns the gene KRAS and lung adenocarcinoma.