In addition, ceRNA interactions including RP11-363E7.4/TTN-AS1/HOTAIRM1-hsa-miR-106b-5p-PTGER3 and LINC00960-hsa-miR-1237-3p-MMP-2 might be of novel and great value for clearing the pathogenesis and progression of DN. Here, PTGER3 is linked to liver dysplastic nodule.