Many non-coding RNAs and genes like transforming growth factor (TGF) β, nephrin, angiotensin-converting enzyme-2, interleukin-6 (IL-6), and tumor necrosis factor (TNF)-α have been identified to be associated with the development, progression, and prognosis of DN [9, 12–14]. This evidence concerns the gene IL6 and liver dysplastic nodule.