As well, miR-484 promotes neurogenesis by targeting PCDH19 [273], prevents ischemia-reperfusion injury by inhibiting CAS3 and CAS9 mediated apoptosis of myocardial cells in rats [274], creates resistance to sunitinib mediated therapy in metastatic renal carcinoma [189] and reverses cytidine deaminase axis (CDA)-mediated chemoresistance in breast cancer [190]. This evidence concerns the gene CDA and breast carcinoma.