To date, mutations in ten genes have been identified to cause ARCI: TGM1 (MIM 190195) [2], ALOX12B (MIM 603741) [3], ALOXE3 (MIM 607206) [3], NIPAL4/ICHTHYIN (MIM 609383) [4], CYP4F22 (MIM 611495) [5], ABCA12 (MIM 607800) [6], PNPLA1 (MIM 612121) [7], CERS3 (MIM 615276) [8], SDR9C7 (MIM 609769) [9], and SULT2B1 (MIM 604125) [10]. The gene discussed is ABCA12; the disease is autosomal recessive congenital ichthyosis.