CDKN2A and acute lymphoblastic leukemia: Most studies of pediatric cohorts show that CDKN2A/B deletions have no prognostic relevance in T-ALL (Table 1), with the exception of the NOPHO (Nordic Society of Paedriatic Haematology and Oncology) cohort study, in which deletions in the CDKN2A/B gene cluster were associated with lower OS.