CUL3 and neoplasm: However, we corroborated the tumor-suppressive roles of insertions in Adk and Zbtb20 and in Nipbl, Pdlim5, Ppp1r12a, Tnrc6b, Brd4, Cul3, Ctnna3, Elavl1, Gphn, Nfia, Ptpn12, Taok3, and Rasa1 (Figure 4).