Widely available and inexpensive biomarkers of liver fibrosis include AST-to-ALT ratio (AAR), AST-to platelet ratio index (APRI), Fibrosis-4 (FIB-4), and Forns index, all of which have been applied in patients with chronic liver disease owing to different aetiologies [21,23]. The gene discussed is GPT; the disease is Hepatic fibrosis.