As exhibited in Figure 1B, LH displayed a preferential anti-proliferative activity against the four pancreatic cancer cell lines in a dose-dependent manner with IC50 values of 3.21, 0.67, 2.78, and 5.53 μM in PANC-1, SW1990, AsPC-1, and BxPC-3 respectively after 48 h. Here, PLOD1 is linked to familial pancreatic carcinoma.