It has been suggested that AIFM3 expression is a direct target of miR-210 [25,26], whereas the down-regulation of miR-210 and the increased expression of AIFM3 inhibits proliferation, induces apoptosis and enhances radiosensitivity in hypoxic human hepatoma cells in vitro [25]. Here, AIFM3 is linked to hepatocellular carcinoma.