AIFM3 and cancer: The functional analysis performed using databases and enrichment analysis confirmed AIFM3 copy number gain and gene overexpression in several cancer subtypes (Catalogue of Somatic Mutations in Cancer (COSMIC), Table S3), while very low expression levels have been observed in several normal tissues, including thyroid, adrenal, prostate, liver, lung, and others (GTEX, FANTOM5 and Human Protein Atlas dataset).