Furthermore, some studies have revealed that MM cells secrete cytokines such as CCL5, MIP-1α [170] and large amounts of IL-6 when MDSCs are present [167,170,173], suggesting that not only do MDSCs contribute to MM progression by direct cell–cell contact or exosome intercellular communication, but also through cytokine secretion. The gene discussed is CCL3; the disease is Miyoshi myopathy.