Similar studies of genome-wide profiles of miRNAs in the tumor of mice bearing Lewis lung carcinoma (LLC) have been performed, after treatment with RNase A, by high-throughput Sequencing by Oligonucleotide Ligation and Detection (SOLiDTM) sequencing technology and RT-qPCR by Mironova et al. [54]. Here, RNASE1 is linked to neoplasm.