Additionally, the elevation of acyl-CoA oxidase 1 (ACOX1), carnitine palmitoyltransferase 1A (CPT1A) and low-density lipoprotein receptor (LDLR), and the inhibition of 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR) indicated the attenuation of hyperlipidemia. Here, HMGCR is linked to hyperlipidemia.