For example, using serological analysis of recombinant cDNA expression libraries (SEREX) in combination with phage display technology, a panel of serum autoantigens consisting of galectin 3 (LGALS3), prohibitin 2 (PHB2), MUC1, glycerol kinase 2 (GK2), and CA 15–3 demonstrated better diagnostic values for early-stage breast cancer compared to anti-CA 15–3 alone [88]. This evidence concerns the gene GK2 and breast carcinoma.