An in vivo study on mice injected with inflammatory breast cancer (IBC) and treated with the commercial extract ReishiMax GLpTM (carpophore and cracked spores) highlighted a selective action on gene and protein expression, with smaller tumor size and weight and reduced expression of E-cadherin, mammalian target of rapamycin (mTOR), human eukaryotic translation initiation factor 4G (eIF4G), and p70 ribosomal protein S6 kinase (p70S6K) and the activity of extracellular regulated kinase (ERK 1/2) [8]. This evidence concerns the gene RPS6KB1 and inflammatory breast carcinoma.