In a randomized, double-blind, placebo-controlled trial, subjects with advanced non-small cell lung cancer (NSCLC) who received PSP for 28 days following chemotherapy showed a significant improvement in blood leukocyte and neutrophil counts, serum IgG and IgM, and body fat percentage compared to the control group, resulting in a slower general deterioration [75]. The gene discussed is CD40LG; the disease is non-small cell lung carcinoma.