In a subsequent study in rodent LM3 mammary adenocarcinoma cells, it was observed that D-fraction, in addition to inducing apoptosis and reducing cell motility and invasiveness, increased cell adhesion by upregulating E-cadherin protein levels and inhibiting matrix metalloproteinase-2 (MMP-2) activity [39], while in triple-negative breast cancer (TNBC) cells, in addition to the effects just described, it also suppressed MMP-9 and reduced cell–cell adhesion by also increasing the membrane localization of the β-catenin protein [40]. The gene discussed is MMP2; the disease is triple-negative breast carcinoma.