A total of 29 CRCs (72.5%) showed loss of expression of at least 1 MMR protein (Table S1): MLH1/PMS2 in 21 tumors, MSH2/MSH6 in 3 tumors, MLH1/PMS2/MSH6 in two tumors, PMS2 in 1 tumor, MSH6 in one tumor, and MLH1/PMS2/MSH2/MSH6 in 1 tumor. The gene discussed is MSH2; the disease is neoplasm.