Combined treatment of ginger and Gelam honey was more effective than treatments with either Gelam honey only or ginger only in inhibiting the growth of HT29 colon cancer cells by inducing early apoptosis, modulating the expression of genes involved in the KRAS/ERK/ PI3K/AKT pathways and suppressing inflammation via the NFκB pathway. This evidence concerns the gene NFKB1 and colonic neoplasm.