In summary: (1) we found correlations for 25(OH)D and AA with the EDSS (opposite effects), (2) a positive correlation between PA/AA ratio and 25(OH)D (Table 4) was also found in MS patients, (3) a positive correlation was found for 25(OH)D and PA with CD8+ T (TD) cells among HC and (4) correlations were also found between PA and AA with IL-17-producing CD8+ T cells (positive correlation) and with TNF-α-producing CD19+ cells and naïve CD4+ T-cells (negative correlation y both cases) in MS patients. This evidence concerns the gene IL17A and myeloid sarcoma.