Moreover, to determine whether knockdown of c-Jun inhibited the mRNA and protein expression of LAMB1 in gastric cancer, we treated AGS and MKN-28 cells with JUN-specific siRNAs and found that c-Jun knockdown decreased LAMB1 expression at both mRNA and protein levels in AGS and MKN-28 cells (Figure 6E). This evidence concerns the gene LAMB1 and gastric cancer.