KDM4D and colitis: JMJD2D has been reported to play important roles in androgen target genes activation, DNA damage repair, DNA replication, somatic cell nuclear transfer (SCNT), colitis, and colorectal, liver, and gastrointestinal stromal cancers (21, 22, 23, 24, 25, 26, 27, 28); however, the role of JMJD2D in CSCs remains unclear.