Based on its neighborhood genomic location, binomial‐transcripts (LncRNAs/mRNAs) were identified in a co‐expressed pattern, highlighting that SOX2‐OT/SOX2, and GLI1‐AS/GLI‐1 in human lung cancer cells and solid lung carcinomas probably engage in a dynamic positive/negative correlation, as has been previously reported for prostate and breast carcinomas [33, 34]. This evidence concerns the gene SOX2 and lung cancer.