RIGI and enterovirus infectious disease: Eleven cellular factors that are known to be cleaved during enterovirus infection were identified using this approach, including the viral sensor Probable ATP-dependent RNA helicase DDX58 (RIG1), the immune transcription factors p65 (RELA) and interferon regulatory factor 7 (IRF7), and polyadenylate-binding protein 1 (PABPC1), an important factor in translation initiation and mRNA stability (Supplementary file 8; Jagdeo et al., 2018; Laitinen et al., 2016).