Hepatobiliary contrast agent retention in the HBP occurs in 83%, 19%, 0% and 0% of β-catenin, inflammatory, HNF1α-inactivated and unclassified HCAs, respectively [44], and it is helpful to distinguish all higher-risk HCA and HCA–HCC with 100% accuracy [45]. This evidence concerns the gene HNF1A and hepatocellular adenoma.