However, incomplete inhibition of ZIKV infection in cells pre-treated with an anti GRP78 N-terminal antibody and no effect of down regulation of GRP78 to viral binding or/and entry level may suggest that ZIKV uses multiple molecules during entry into the cell, consistent with previous studies that have characterized AXL as ZIKV receptor on A549 cells17. The gene discussed is HSPA5; the disease is Zika virus infectious disease.