Statistical analysis showed that the mutational frequencies of NF1 (P = 0.0024), NOTCH3 (P = 0.004), PRKCI (4.49 × 10–6), TERT (4.44 × 10–7), FAM135B (0.008), MYC (4.44 × 10–7), NOTCH1 (2.71 × 10–5), and PTK2 (4.49 × 10–6) in Chinese ovarian cancer patients were significantly higher than those in Western patients (Fig. 3A). This evidence concerns the gene NOTCH1 and ovarian cancer.