PEG3, ZNF365, HERC1, FBXW7, TERF2IP, STAT4, NLK, RBFOX2, CDK5, POLR2K, PSMD12 were gained in the AD samples, whereas BZW2, RNF6, ZBTB11, SORBS3, TRIM56, MORF4L1, CNOT7, RBCK1, SMYD3, RAN, KLHL12, ZC3H15, and EID1 were lost in the AD samples. This evidence concerns the gene HERC1 and Alzheimer disease.